Monday, November 30, 2020

New Study Indicates that Covid-19 Fatality Rate has Dropped 30% Since April 2020

 

 

In the early days of the Covid-19 pandemic, the fear on everyone’s mind was the fatality rate.  With so little known about the disease in those first few weeks, the general public was terrified… and rightfully so.  It seemed to practically be a death sentence.  That may have been due to media focus on overwhelmed hospitals or simply fear of the unknown, but no matter the source, the fear was real and often palpable.  I distinctly remember a meeting with my staff in March where we were discussing how the world was rapidly changing due to infections.  At that meeting, many staff indicated their concerns about the risks that were (and still are) inherent in the practice of dentistry.  Many were concerned, not only about their personal health, but the health of their families if they somehow managed to become exposed and take the infection home.  

 


Now we are approaching a year since the SARS-CoV-2 virus first appeared in Wuhan China.  While infection rates in the U.S. have continued to climb in a near exponential fashion, fatality rates have not increased at the same proportion as infections.  A lot of this has to do with the incredible amount of study and the distribution of this knowledge that has been done by the world’s leading infectious disease experts.  This has lead to an incredible number of lives saved.  While Covid-19 remains a serious threat, at least we have learned how to help more people recover.

 

 A recent story on Reuters states the following:

 

(Reuters) - The likelihood that a coronavirus infection will prove fatal has dropped by nearly a third since April due to improved treatment, researchers at the University of Washington’s Institute for Health Metrics and Evaluation (IHME) said on Thursday.

In the United States, COVID-19 now kills about 0.6% of people infected with the virus, compared with around 0.9% early in the pandemic, IHME Director Dr. Christopher Murray told Reuters.

He said statistics reflect that doctors have figured out better ways to care for patients, including the use of blood thinners and oxygen support. Effective treatments, such as the generic steroid dexamethasone, have also been identified.

Experts have struggled to accurately measure a crucial metric in the pandemic: the fatality rate, or percentage of people infected with the pathogen who are likely to die. The difficulty is exacerbated by the fact that many people who become infected do not experience symptoms and are never identified.

IHME said it had been using an infection-fatality rate (IFR) derived from surveys after accounting for age. Older people are at much higher risk of dying from COVID-19 than younger people.

“We know the risk is profoundly age-related. For every one year of age, the risk of death increases by 9%,” Murray said.

The Seattle institute, an influential source of COVID-19 forecasts, said it has also determined that the fatality rate for COVID-19 is worse in communities with high levels of obesity.

The group said it has now switched to an IFR that varies over time - declining since the first pandemic wave in March and April by around 0.19% per day until the beginning of September.

It also varies across locations as a function of obesity prevalence, and continues to vary based on population distribution by age.

IHME said its analysis of age-standardized fatality rates from more than 300 surveys suggests a 30% decline since March/April.

Despite that positive trend, infections and hospitalizations have spiked across the country in recent weeks. The group said its modeling suggests 439,000 cumulative U.S. deaths by March 1, and a peak of daily deaths in mid-January at 2,200.

 

The University of Washington’s Institute for  Health Metrics and Evaluation has some amazing data and graphical ways of viewing that data.  If you have any interest in projections of the Covid-19 pandemic, I highly advised giving this site a visit.

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