Wednesday, March 28, 2018

Study of Oral Moisturizers Concludes that OraCoat® XyliMelts® Contain One of the Safest pH Levels of any US OTC Dry Mouth Product


University of Florida Study of Eleven Brands of Lozenge-Type Oral Moisturizers Finds that Most have Dangerous Acidity Levels with XyliMelts being One of the Few Exceptions

 – Researchers at the University of Florida recently tested eleven brands of lozenge-type oral moisturizers for harmful acidity levels that cause tooth erosion. The study found that nine of the eleven tested products are acidic (pH less than 7) and cause tooth erosion. The only two lozenge-type dry mouth remedies that were non-acidic were OraCoat® XyliMelts® and Salese®.

The objective of the study was to measure pH levels, titratable acidity, and erosive effect of commercially distributed dry mouth lozenges and adhering discs on teeth, mainly the dentin which is exposed at the gumline. Each product was crushed into five grams of powder and dissolved in 10 mL of water. Acidity was measured with a calibrated pH meter. Titratable acidity was measured by adding sodium hydroxide until the solution reached neutrality. Erosion of tooth structure was measured by placing human teeth in the solution and measuring loss of mass.

In order of danger, the most dangerously acidic dry mouth lozenges and adhering discs were reported to be:

• DenTek® OraMoist®, pH 2.9
• Cotton Mouth Lozenges®, pH 3.1
• MedActive® Oral Relief Lozenges, pH 3.2
• Hager Pharma Dry Mouth Drops, pH 4.44
• Rite Aid Dry Mouth Discs, pH 5.1
• CVS Dry Mouth Discs, pH 5.3
• ACT® Dry Mouth Lozenges, pH 5.7
• TheraBreath Dry Mouth Lozenges, pH 5.82

Moreover, the oral moisturizers that caused the most tooth erosion were, in order:

• Cotton Mouth Lozenges, 3.1% loss
• DenTek OraMoist, 2.3% loss
• MedActive Oral Relief Lozenges, 1.1% loss
• Rite Aid Dry Mouth Discs, 1.1% loss
• CVS Dry Mouth Discs, 1.0% loss
• TheraBreath Dry Mouth Lozenges, 1.0% loss

The study found a robust statistical correlation between high acidity and tooth loss. Both remedies that passed the acidity test, XyliMelts and Salese, contain a pH level of 8.0, which is considered non-harmful to teeth. Previous studies reported that pH below 6.7 can be erosive to dentin. One of the products, XyliMelts discs, was recently revealed to reduce symptoms of Gastroesophageal Reflux Disease (GERD), which also causes tooth erosion. XyliMelts are oral adhering discs that contain 550 mg of xylitol for sweetness to stimulate saliva flow, cellulose gum to slow dissolution and lubricate the mouth, a layer of acacia gum to adhere to gingiva or teeth, and a small amount of calcium carbonate to neutralize acidity. XyliMelts used at night while sleeping is the most effective per gram delivery of xylitol to reduce tooth decay.
The complete study results are available at this link:
XyliMelts are available over the counter at Walmart, CVS, and Rite Aid. For more information on XyliMelts, visit

About OraCoat
OraCoat is the world leader in the breakthrough technology of “oral adhering discs” which slowly release ingredients in the mouth and are safe for use while sleeping. The OraCoat® brand represents a family of products that solve oral care problems by coating the mouth with safe ingredients that become effective when they are slowly released. OraCoat’s leading products are XyliMelts® and XyliGel® OTC products for dry mouth. Other oral care solutions in the OraCoat family are planned. OraCoat’s innovative oral care solutions are backed by careful research based on medical science to ensure optimum performance and user safety.


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