Monday, August 31, 2015

Medical Marijuana: An Extensive Review of Clinical Benefits and Adverse Effects

A recent study by Whiting, et al, (JAMA 2015) performed an extensive literature review using 28 databases and provided assessment of the indications, benefits and adverse effects of medical marijuana and cannabinoids. Using a rating scale to score the quality of evidence, the authors described evidence of moderate quality to support the use of marijuana in treating chronic pain syndromes and spasticity from multiple sclerosis. There was evidence of low quality that cannabinoids were associated with some improvements in chemotherapy-induced nausea and vomiting, sleep disorders, weight gain in HIV infection, and Tourette syndrome. Indications for which cannabinoids showed either very low-quality evidence or no effect included CNS depression, anxiety disorder, psychosis, and intraocular pressure from glaucoma. Adverse effects were reported with the use of cannabinoids, including, among others, dizziness, dry mouth, nausea, fatigue, somnolence, euphoria, drowsiness, confusion, loss of balance and hallucination.

I found this a pretty interesting read.  The full article is here.  

No comments:

Post a Comment