Friday, November 8, 2013

Could Aspirin Aid in Decreasing Periodontal Pocketing?

A story that was originally out in 2012, made the rounds again  here in 2013 (the power of the Internet).  The story came from a study published in 2012 by the Australian Dental Journal.
The idea is/was does a small daily dose of aspirin cause a reduction in periodontal pocketing?
The study was comprised of  2 "aspirin" groups and one control group.   The  aspirin groups were divided into one group taking 75mg per day while the other was taking 150mg per day.  The total number of these patients was 152 individuals.  The control group was 146 who did not take  any aspirin at all.  Comparisons were made between all 3 groups.
It was noted the aspirin group averaged about .25mm less pocket depth.  Which was statistically significant, but I would leave it to statisticians to determine if it is clinically significant.  There is a difference between the two and I'm not sure where that differentiation lies.
The study was cited on the website & I did notice some info on the site that I would take issue with.  I'm not sure, but some of the wording seemed to indicate the site might be run by a layperson or laypeople, which , in that case, would explain the odd terminologies.
While doing a little research on PubMed, I found what I think to be the original Australian study (no authors were mentioned on the worldental site).  The conclusions on PubMed stated "The results of this study suggest that low dose aspirin may reduce the risk of periodontal attachment loss. This hypothesis needs to be tested by larger sample sized prospective cohort studies."
My point in listing the conclusion is that the authors suggest this needs more research and more patients to fully examine  the possibilities.  I agree with this.  Small sample sizes just aren't enough to get conclusive results.

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