Thursday, December 22, 2011

New Chemistry Developed that Creates Fluorescence in Cancer Cells


Fluorescent cells.jpg
Here is a pretty interesting discovery that may make detection of cancer cells easier for both diagnosis and surgical excision. The reagent was developed by a team at the University of Tokyo   and the National Institute of Health.
The reagent allows detection of cancerous cells smaller than 1 mm. The resulting glow is 20 times brighter on cancerous cells than on noncancerous cells allowing for much easier detection. This means that in the future it may be possible to find tumors at sizes smaller than can be detected by conventional means today.
This could allow for better diagnosis of tiny lesions as well as aiding surgeons in removing as little healthy tissue as possible if excision is required.
In dentistry today, we are currently using fluorescent devices such as the DOE from Dentlight, the Velscope VX from LED Dental, and the Identafi from DentalEZ  to  aid in the early detection of oral cancers. However, these devices cause fluorescence of healthy tissue while questionable areas remained dark. These dental devices also use light only and require no use of any chemicals.
Here's hoping that this new reagent can have an impact in early detection as well as less invasive surgery.

For the full story, read about the discovery at